[{"omimId":113800,"diseaseName":"Bullous congenital ichthyosiform erythroderma/Epidermolytic hyperkeratosis","diseaseAbbr":"BCIE/EHK","introduce":"BCIE/EHK also names Bullous congenital ichthyosiform erythroderma/Epidermolytic hyperkeratosis. It is a typical genodermatosis and caused by sequence variants in K1/K10.  The phenotype of the proband is diagnosed as erythema and widespread formation of epidermal blisters at birth. And later in life, bullous erythema is replaced by progressive hyperkeratosis, involving thickening of the cornified layer of the epidermis (From OMIM)."},{"omimId":607602,"diseaseName":"Ichthyosis, cyclic, with epidermolytic hyperkeratosis","diseaseAbbr":"CIEH","introduce":"CIEH also names Ichthyosis, cyclic, with epidermolytic hyperkeratosis. It is a genodermatosis and caused by sequence variants in K1/K10.  The phenotype of the proband is diagnosed as epidermolytic hyperkeratosis and also palmoplantar hyperkeratosis (From OMIM)."},{"omimId":144200,"diseaseName":"Palmoplantar keratoderma, epidermolytic/Greither's syndrome","diseaseAbbr":"EPPK/GS","introduce":"EPPK/GS also names Palmoplantar keratoderma, epidermolytic/Greither's syndrome. It is a typical genodermatosis and caused by sequence variants in K1/K9, especially in K9. It is a branch of Palmoplantar keratodermas (PPK). The proband of Palmoplantar keratodermas (PPK) is diagnosed as hyperkeratosis on the surface of palms and soles (From OMIM)."},{"omimId":146590,"diseaseName":"Ichthyosis hystrix, Curth-Macklin type","diseaseAbbr":"IHCM","introduce":"IHCM also names Ichthyosis hystrix, Curth-Macklin type. It is a genodermatosis, one type of ichthyosis and caused by sequence variants in K1/K10, especially in K1."},{"omimId":600962,"diseaseName":"Palmoplantar keratoderma, nonepidermolytic","diseaseAbbr":"NEPPK","introduce":"NEPPK also names Palmoplantar keratoderma, nonepidermolytic. It is a genodermatosis and caused by sequence variants in K1.  It is a branch of Palmoplantar keratodermas (PPK). The proband of Palmoplantar keratodermas (PPK) is diagnosed as hyperkeratosis on the surface of palms and soles (From OMIM)."},{"omimId":613000,"diseaseName":"Palmoplantar keratoderma, nonepidermolytic, focal 1","diseaseAbbr":"FNEPPK1","introduce":"FNEPPK1 also names Palmoplantar keratoderma, nonepidermolytic, focal 1. It is a genodermatosis and caused by sequence variants in K16."},{"omimId":179850,"diseaseName":"Dowling-Degos disease 1","diseaseAbbr":"DDD1","introduce":"DDD1 also names Dowling-Degos disease 1. It is an autosomal dominant genodermatosis and caused by sequence variants in K5. The phenotype of the proband is diagnosed as reticular pigmentation (From OMIM)."},{"omimId":131960,"diseaseName":"Epidermolysis bullosa simplex with mottled pigmentation","diseaseAbbr":"EBS-MP","introduce":"EBS-MP also names Epidermolysis bullosa simplex with mottled pigmentation. It is a genodermatosis and caused by sequence variants in K5/K14, especially K5."},{"omimId":131760,"diseaseName":"Epidermolysis bullosa simplex, Dowling-Meara type","diseaseAbbr":"EBS-DM","introduce":"EBS-DM also names Epidermolysis bullosa simplex, Dowling-Meara type. It is a genodermatosis and caused by sequence variants in K5/K14. It is a branch of Epidermolysis bullosa simplex (EBS). The proband of Epidermolysis bullosa simplex (EBS) is diagnosed as recurrent blistering of the skin just for minor physical trauma (From OMIM). And EBS-DM is the most severe form of EBS."},{"omimId":131900,"diseaseName":"Epidermolysis bullosa simplex, Koebner type/Recessive pidermolysis bullosa simplex, Koebner type","diseaseAbbr":"EBS-K/REBS-K","introduce":"EBS-K/REBS-K names Epidermolysis bullosa simplex, Koebner type/Recessive pidermolysis bullosa simplex, Koebner type, and also Epidermolysis bullosa simplex, generalized. It is a genodermatosis and caused by sequence variants in K5/K14. It is a branch of Epidermolysis bullosa simplex (EBS). The proband of Epidermolysis bullosa simplex (EBS) is diagnosed as recurrent blistering of the skin just for minor physical trauma (From OMIM). And EBS-K is the milder form of EBS than EBS-DM."},{"omimId":131800,"diseaseName":"Epidermolysis bullosa simplex, Weber-Cockayne type/Recessive epidermolysis bullosa simplex, Weber-Cockayne type","diseaseAbbr":"EBS-WC/REBS-WC","introduce":"EBS-WC/REBS-WC names Epidermolysis bullosa simplex, Weber-Cockayne type/Recessive epidermolysis bullosa simplex, Weber-Cockayne type, and also epidermolysis bullosa simplex, localized. It is a genodermatosis and caused by sequence variants in K5/K14. It is a branch of Epidermolysis bullosa simplex (EBS). The proband of Epidermolysis bullosa simplex (EBS) is diagnosed as recurrent blistering of the skin just for minor physical trauma (From OMIM). And EBS-WC is the mild and localized form of EBS."},{"omimId":125595,"diseaseName":"Dermatopathia pigmentosa reticularis","diseaseAbbr":"DPR","introduce":"DPR also names Dermatopathia pigmentosa reticularis. It is a rare genodermatosis and caused by sequence variants in K14. The phenotype of the proband is diagnosed as reticulate hyperpigmentation, noncicatricial alopecia, and onychodystrophy and so on."},{"omimId":161000,"diseaseName":"Naegeli-Franceschetti-Jadassohn syndrome","diseaseAbbr":"NFJS","introduce":"NFJS also names Naegeli-Franceschetti-Jadassohn syndrome.  It is a genodermatosis and caused by sequence variants in K14."},{"omimId":601001,"diseaseName":"Epidermolysis bullosa simplex, autosomal recessive 1","diseaseAbbr":"EBSB1","introduce":"EBSB1 also names Epidermolysis bullosa simplex, autosomal recessive 1. It is a genodermatosis and caused by sequence variants in K5/K14."},{"omimId":146800,"diseaseName":"Ichthyosis bullosa of Siemens","diseaseAbbr":"IBS","introduce":"IBS also names Ichthyosis bullosa of Siemens. It is a rare autosomal dominant genodermatosis and caused by sequence variants in K2."},{"omimId":167200,"diseaseName":"Pachyonychia congenita 1","diseaseAbbr":"PC-1","introduce":"PC-1 also names Pachyonychia congenita 1. It is an autosomal dominant genodermatosis and caused by sequence variants in K6a and K16. The phenotype of the proband is diagnosed as hypertrophic nail dystrophy, painful and highly debilitating plantar keratoderma, oral leukokeratosis and a variety of epidermal cysts."},{"omimId":167210,"diseaseName":"Pachyonychia congenita 2","diseaseAbbr":"PC-2","introduce":"PC-2 also names Pachyonychia congenita 2. It is an autosomal dominant genodermatosis and caused by sequence variants in K6b and K17. The phenotype of the proband is diagnosed as hypertrophic nail dystrophy, painful and highly debilitating plantar keratoderma, oral leukokeratosis and a variety of epidermal cysts."},{"omimId":184500,"diseaseName":"Steatocystoma multiplex","diseaseAbbr":"SM","introduce":"SM also names Steatocystoma multiplex. It is a disease caused by sequence variants in K17."},{"omimId":615726,"diseaseName":"Pachyonychia Congenita-K6a ","diseaseAbbr":"PC-K6a","introduce":"PC-K6a also names Pachyonychia Congenita-K6a.  It is a genodermatosis and caused by sequence variants in K6a."},{"omimId":615728,"diseaseName":"Pachyonychia Congenita-K6b ","diseaseAbbr":"PC-K6b","introduce":"PC-K6b also names Pachyonychia Congenita-K6b. It is a genodermatosis and caused by sequence variants in K6b."},{"omimId":167200,"diseaseName":"Pachyonychia Congenita-K16","diseaseAbbr":"PC-K16","introduce":"PC-K16 also names Pachyonychia Congenita-K16. It is a genodermatosis and caused by sequence variants in K16."},{"omimId":167210,"diseaseName":"Pachyonychia Congenita-K17","diseaseAbbr":"PC-K17","introduce":"PC-K17 also names Pachyonychia Congenita-K17. It is a genodermatosis and caused by sequence variants in K17."},{"omimId":10,"diseaseName":"Palmoplantar keratoderma and mild ichthyosis","diseaseAbbr":"Palmoplantar keratoderma and mild ichthyosis","introduce":"Palmoplantar keratoderma and mild ichthyosis is caused by sequence variants in K1. The proband of Palmoplantar keratodermas (PPK) is diagnosed as hyperkeratosis on the surface of palms and soles."},{"omimId":11,"diseaseName":"Epidermolysis bullosa simplex with severe palmoplantar hyperkeratosis","diseaseAbbr":"Epidermolysis bullosa simplex with severe palmoplantar hyperkeratosis","introduce":"Epidermolysis bullosa simplex with severe palmoplantar hyperkeratosis is caused by sequence variants in K5. The proband of Epidermolysis bullosa simplex (EBS) is diagnosed as recurrent blistering of the skin just for minor physical trauma."},{"omimId":12,"diseaseName":"Epidermolysis bullosa simplex with unknown subtype","diseaseAbbr":"Epidermolysis bullosa simplex with unknown subtype","introduce":"Epidermolysis bullosa simplex with unknown subtype is caused by sequence variants in K5. The proband of Epidermolysis bullosa simplex (EBS) is diagnosed as recurrent blistering of the skin just for minor physical trauma."},{"omimId":13,"diseaseName":"Palmoplantar keratodermas","diseaseAbbr":"PPK","introduce":"PPK also names Palmoplantar keratoderma. It is a typical genodermatosis and caused by sequence variants in K1. The proband of Palmoplantar keratodermas (PPK) is diagnosed as hyperkeratosis on the surface of palms and soles."},{"omimId":14,"diseaseName":"Epidermolytic Nevus","diseaseAbbr":"EN","introduce":"EN also names epidermolytic nevus. It is a mosaic disease and caused by sequence variants in K1, K2 and K10. The proband of epidermolytic nevus (EN) is diagnosed as hyperkeratotic verrucous streaks."}]